Global Sanger Sequencing Market Set to Grow at Highest Pace owing to Rising Application of Sanger Sequencing in Clinical Diagnostics

 

Global Sanger Sequencing Market

Sanger sequencing plays an important role in mapping DNA sequences and gaining insights into the genetics of various diseases. Some of the key applications of Sanger sequencing include identifying and mapping of the human genome, clinical diagnostics of genetic disorders, forensic analysis, and targeted re-sequencing projects. The non-commercial open-source databases created with Sanger sequencing technology have significantly contributed to advances in life sciences research.

The Global Sanger Sequencing Market is estimated to be valued at US$ 10,130.6 Mn in 2024 and is expected to exhibit a CAGR of 18% over the forecast period 2024 to 2031.

Key Takeaways

Key players operating in the Global Sanger Sequencing Market are Eurofins Scientific, CeMIA, Fasteris SA, GENEWIZ, GenHunter Corporation, GenScript, LGC Biosearch Technologies, Nucleics, Quintara Biosciences, SciGenom Labs Pvt. Ltd, StarSEQ GmbH, Thermo Fisher Scientific Inc., QIAGEN, Promega Corporation, and Source BioScience. Eurofins Scientific and Thermo Fisher Scientific Inc capture over 30% of the market share due to their diversified product portfolio and strong global presence.

The rising application of Sanger sequencing in clinical diagnostics of genetic disorders is a major factor driving the growth of this market. Sanger sequencing helps in the identification of single-nucleotide variants and small mutations responsible for genetic disorders. Moreover, the continuous decline in the cost of sequencing has made Sanger sequencing an affordable method for clinical diagnosis, further boosting the market growth.
Technological advancements including automated sequencing platforms, web-based sequencing analysis tools, and workflow management software are augmenting the capabilities of Sanger sequencing. The development of enhanced chemistries for fluorescence-based sequencing and instruments with higher throughput is expanding the application range of Sanger sequencing.

Market Trends

Next-generation Sequencing gaining traction - While Sanger sequencing still dominates the clinical diagnostics sector, next-generation sequencing (NGS) technologies are gaining increased acceptance in research and drug discovery due to their high-throughput and cost-effective nature. In the coming years, NGS technologies are expected to capture a part of the market share held by Sanger sequencing.
Application in drug discovery and precision medicine - Sanger sequencing continues to find new use cases in understanding disease pathophysiology at a molecular level and advancing personalized treatment strategies. It plays a vital role in pharmacogenomics and companion diagnostic development. The growing need for precision medicine is expected to boost the demand for Sanger sequencing.

Market Opportunities

Clinical applications in developing countries - Most developing markets still rely on Sanger sequencing for clinical genetic testing due to its affordability and relevance for analysis of targeted genomic regions. The rapidly growing healthcare infrastructure and increasing focus on genetic/rare disorder diagnosis in developing countries will provide significant opportunities.
Sanger sequencing as gold standard - Despite the emergence of NGS, Sanger sequencing continues to be indispensable where high accuracy is required, such as in clinical diagnosis. Sanger sequencing enjoys a solid reputation of being the gold standard sequencing method that will help it stay relevant for years to come.
Impact of COVID-19 on Global Sanger Sequencing Market Growth

The COVID-19 pandemic has positively impacted the growth of the global Sanger sequencing market. During the pandemic, research institutions and pharmaceutical companies ramped up their efforts on SARS-CoV-2 genome sequencing to track virus mutations and develop vaccines and therapeutics. Also, hospitals extensively used Sanger sequencing for genetic and infectious disease diagnostics of COVID-19 patients.

In the pre-COVID era, Sanger sequencing was predominantly used in research applications like detection of genetic disorders and study of human genome variations. However, during the pandemic, its diagnostic use increased significantly. Research funding bodies made additional grants available for genomic research on COVID-19. This boosted the demand for high-throughput Sanger sequencing products and services among academia and industry.

The post-COVID scenario indicates that demand for Sanger sequencing may gradually shift back to research as pandemic related sequencing requirements decline. However, diagnostic usage is expected to remain high due to increased focus on infectious disease monitoring and preparedness. Market players are likely to witness growth opportunities in developing sequencing kits and panels for routine screening of pathogens. Capacity expansions and technology upgrades would help them serve the growing diagnostic sequencing market on a long-term basis.

Geographical Regions with High Concentration of Global Sanger Sequencing Market Value

North America accounts for the largest share of the global Sanger sequencing market in terms of value. Presence of many leading market players, massive research funding, and advanced healthcare infrastructure have contributed to North America's dominance. Growth in genomics-driven diagnostics and therapeutics development is driving sequencing equipment procurement and services adoption in the region.
Asia Pacific is projected to be the fastest growing regional market during the forecast period. This is attributed to increasing R&D expenditures, focus on agriculture and animal genetics research, and expandingDiagnostics industry. Rising awareness, improving access, and government initiatives are encouraging life science organizations across China, India, Japan and South Korea to investmore in genomic technologies like Sanger sequencing.

Fastest Growing Regional Market for Global Sanger Sequencing Market

Asia Pacific is anticipated to be the fastest growing regional market for Sanger sequencing during the forecast years. Rising penetration of next-generation sequencing technologies is driving the demand for Sanger sequencing in emerging Asia Pacific countries. Further, large population with increasing incidence of genetic disorders and growth in medical tourism are propelling diagnostic applications of sequencing. Substantial funding for agricultural and clinical research from governments and private entities offers significant opportunities. In addition, presence of low-cost skilled workforces is attracting sequencing product manufacturers and service providers to set up facilities in Asia Pacific. All these factors will significantly contribute to the fast growth of this regional market in the coming years.

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